AI and conversation bots are one of the most competitive domains in computer science. Such applications utilize both machine learning and NLP techniques to build intelligent dialog machines, which can make conversation with human beings. The speaker in this talk has given the introduction of the current progress in making conversation bots, and discussed about virtual humans and the interactive conversation technologies. He shared some promising applications where we may play “conversation games” with those virtual humans. The type of conversation is not easy ones of daily talk, but with some domains that require expert knowledge medical conversations or interview talks.